Recent Publication
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Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions
Nature Communications / / 2019 / Heo, Won Do
Intensiometric biosensors visualize the activity of multiple small GTPases in vivo
Nature Communications / / 2019 / Heo, Won Do
Locally Activating TrkB Receptor Generates Actin Waves and Specifies Axonal Fate
Cell Chemical Biology / / 2019 / Heo, Won Do
Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins
Nature Methods / / 2019 / Heo, Won Do
BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors
Nature Medicine / / 2018 / Heo, Won Do
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
Nature Communications / / 2018 / Heo, Won Do
Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB
Cell Microbiol / / 2018 / Heo, Won Do
Spatiotemporal Control of TGF-β Signaling with Light
ACS Synth Biol / / 2018 / Heo, Won Do
Synergistic Ensemble of Optogenetic Actuators and Dynamic Indicators in Cell Biology
Molecules and Cells / / 2018 / Heo, Won Do
LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate
Frontiers in Molecular Neuroscience / Vol. 10, 327 / 2017 / Heo, Won Do
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
Nature Communications / Vol. 8(30) / 2017 / Heo, Won Do
Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation
Nature Communications / Vol. 8, 14708 / 2017 / Heo, Won Do
APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis
Oncotarget / Vol. 7 / 2016 / Heo, Won Do
Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTPσ Synaptic Adhesion and Intracellular Signaling Pathways
J Neurosci / Vol. 36 / 2016 / Heo, Won Do
Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module
Nature Communications / Vol. 7 / 2016 / Heo, Won Do
PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front
PNAS / Vol. 113 / 2016 / Heo, Won Do
Tracking protein-protein interaction and localization in living cells using a high-affinity molecular binder.
Biochem Biophys Res Commun / Vol. 470 / 2016 / Heo, Won Do
Release of infectious hepatitis C virus from Huh7 cells occurs via a trans-Golgi network to endosome pathway independent of VLDL
J Virol / Vol. 90 / 2016 / Heo, Won Do
Optogenetic toolkit reveals the role of Ca2+ sparklets in coordinated cell migration
PNAS / Vol. 113 / 2016 / Heo, Won Do
Engineering of bacterial exotoxins for highly efficient and receptor-specific intracellular delivery of diverse cargos
Biotechnol Bioeng / Vol. 113 / 2016 / Heo, Won Do
A novel copper-chelating strategy for fluorescent proteins to image dynamic copper fluctuations on live cell surfaces
Chemical Science / vol.6 no.2 / 2015 / Heo, Won Do
Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking
Nature Communications / vol.6 / 2015 / Heo, Won Do
Optogenetic control of endogenous Ca2+ channels in vivo
Nature Biotechnology / vol.33 no.10 / 2015 / Heo, Won Do
Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22
Plose One / vol.10 no.3 / 2015 / Heo, Won Do
Optogenetic control of cell signaling pathway through scattering skull using wavefront shaping
Scientific Reports / vol.5 / 2015 / Heo, Won Do
Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion
Nature Communications / vol.5 / 2014 / Heo, Won Do
Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling
Nature Communications / vol.5 / 2014 / Heo, Won Do
Vascular RhoJ Is an Effective and Selective Target for Tumor Angiogenesis and Vascular Disruption
Cancer Cell / vol.25 / 2014 / Heo, Won Do
Spatiotemporal Control of Fibroblast Growth Factor Receptor Signals by Blue Light
Chemistry & Biology / vol.21 / 2014 / Heo, Won Do
Reversible protein inactivation by optogenetic trapping in cells
Nature Methods / vol.11 / 2014 / Heo, Won Do
Patent
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Process for preparing exosome comprising target protein
Heo, Won Do / 10-2015-0062604 / 2015-05-04 / Patent pending
다능성의 유도 및 세포 재프로그래밍을 위한
고분자 박막 기반의 배양 플랫폼의 제작 및 세
포 배양, 유지 및 증식 방법
Heo, Won Do / 10-2014-0069970 / 2014-09-19 / Patent pending
Fusion proteins capable of activating receptor tyrosine kinase signalling pathway by light and uses thereof
Heo, Won Do / 10-1433057-0000 / 2014-08-18 / Patent approved
Fusion proteins capable of regulating intracellular calcium ion level by light and uses thereof (patent registration
Heo, Won Do / 10-1369853-0000 / 2014-02-26 / Patent approved
Method and kit for reversible inhibiting proteins using light-inducible nanocluster formation
Heo, Won Do / 10-1355970-0000 / 2014-01-21 / Patent approved
Method and kit for analyzing interactions between proteins using light-inducible nanocluster formation
Heo, Won Do / 10-1356787-0000 / 2014-01-21 / Patent approved
Method and kit for analyzing interactions between proteins using light-inducible nanocluster formation
Heo, Won Do / 10-1354601-0000 / 2014-01-16 / Patent approved