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1. Title: [KIB] Peptide Self-Assembly: From Neurodegenerative Diseases to Novel Nanomaterials

2. Date and Time: Thursday, May 22, 2008, 16:00 ~ 17:00

3. Place: Room 2113, Biomedical Research Center (E7)

4. Speaker: Prof. Chan Beum Park (Dept. of Materials Science & Engineering, KAIST)
                 Ph.D. in Chemical Engineering from POSTECH, 1999
                 Lab. homepage: http://biomaterials.kaist.ac.kr
                 Research interests include self-assembled biomaterials,

                 artificial photosynthesis, cofactor regeneration, biosensors & biochips,
                 nanotoxicology, biofunctionalized nanomaterials, etc.

5. Abstract
Self-assembly, a process in which small building blocks spontaneously form fine structures, is centrally important in life and has a great potential for fabricating novel materials as well. The self-assembly of peptides into amyloid aggregates is a pathological hallmark of many neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow, and other life-threatening diseases. Despite many studies on amyloid over a century, a clear understanding on how normal and soluble peptides assemble into amyloid aggregates remains unresolved. In this seminar, following topics about amyloid self-assembly will be discussed:

1) template-directed formation of amyloid aggregates, 2) amyloid lawn system for high-throughput analysis of amyloid toxicity and drug screening. From an engineering point of view, the self-assembly of peptide-based building blocks into nanostructures is an attractive route for fabricating novel bio-inspired materials because of their capacity for molecular recognition and functional flexibility as well as the mild conditions required in the fabrication process. I will introduce our recent development of a novel process for solid-phase growth of vertically well-aligned peptide nanowires having a high aspect ratio and a long persistence length.

List of Articles
No. Category Subject Author Views
67 KIB 총장님 초청 KI for BioCentury 세미나 [2007-01-03] KAIST_INSTITUTE 2306
66 Others 청정에너지연구소-전력연구원(KEPRI)과 전략적파트너쉽형성을 위한 상호협력각서 교환식 [2007-04-06] KAIST_INSTITUTE 2219
65 Others 제 9회 KIUSS 미래도시포럼 [2007-12-13] KAIST_INSTITUTE 2307
64 Others 제 8회 KIUSS 미래도시포럼 [2007-10-18] KAIST_INSTITUTE 2148
63 Others 제 7회 KIUSS 미래도시포럼 [2007-10-12] KAIST_INSTITUTE 1974
62 Others 제 6회 KIUSS 미래도시포럼 [2007-09-20] KAIST_INSTITUTE 2471
61 Others 제 5회 KIUSS 미래도시포럼 [2007-08-23] KAIST_INSTITUTE 2388
60 Others 제 3회 KIUSS 미래도시 포럼 [2007-06-07] KAIST_INSTITUTE 2549
59 Others 제 2회 KIUSS 미래도시 포럼 [2007-04-24] KAIST_INSTITUTE 2031
58 Others 제 2회 KAIST 미래도시 아이디어 공모전 최종발표회 및 시상식 [2008-02-28] KAIST_INSTITUTE 3534
57 Others 미국무부 초청 연사 강연 [2009-07-10] KAIST_INSTITUTE 3493
56 KI The 7th KI Regular Seminar [2008-10-02] file KAIST_INSTITUTE 2393
55 KI The 6th KI Regular Seminar [2008-07-10] KAIST_INSTITUTE 2493
54 KI The 5th KI Regular Seminar [2008-06-26] KAIST_INSTITUTE 2335
53 KI The 4th KI Regular Seminar [2008-06-12] KAIST_INSTITUTE 6686
» KI The 3rd KI Regular Seminar [2008-05-22] KAIST_INSTITUTE 2380
51 KI The 3rd KI International Symposium [2009-09-24] file KAIST_INSTITUTE 3269
50 Others The 2nd KIUSS Seminar [2008-06-23] file KAIST_INSTITUTE 2094
49 KI The 2nd KI Regular Seminar [2008-05-08] KAIST_INSTITUTE 1863
48 KI The 2nd KI International Symposium [2008-09-04] KAIST_INSTITUTE 2418
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