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1. Title: [KIB] Peptide Self-Assembly: From Neurodegenerative Diseases to Novel Nanomaterials
 

2. Date and Time: Thursday, May 22, 2008, 16:00 ~ 17:00

 
3. Place: Room 2113, Biomedical Research Center (E7)
 

4. Speaker: Prof. Chan Beum Park (Dept. of Materials Science & Engineering, KAIST)
                 Ph.D. in Chemical Engineering from POSTECH, 1999
                 Lab. homepage: http://biomaterials.kaist.ac.kr
                 Research interests include self-assembled biomaterials,

                 artificial photosynthesis, cofactor regeneration, biosensors & biochips,
                 nanotoxicology, biofunctionalized nanomaterials, etc.


5. Abstract
Self-assembly, a process in which small building blocks spontaneously form fine structures, is centrally important in life and has a great potential for fabricating novel materials as well. The self-assembly of peptides into amyloid aggregates is a pathological hallmark of many neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow, and other life-threatening diseases. Despite many studies on amyloid over a century, a clear understanding on how normal and soluble peptides assemble into amyloid aggregates remains unresolved. In this seminar, following topics about amyloid self-assembly will be discussed:


1) template-directed formation of amyloid aggregates, 2) amyloid lawn system for high-throughput analysis of amyloid toxicity and drug screening. From an engineering point of view, the self-assembly of peptide-based building blocks into nanostructures is an attractive route for fabricating novel bio-inspired materials because of their capacity for molecular recognition and functional flexibility as well as the mild conditions required in the fabrication process. I will introduce our recent development of a novel process for solid-phase growth of vertically well-aligned peptide nanowires having a high aspect ratio and a long persistence length.





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60 Others 제 2회 KIUSS 미래도시 포럼 [2007-04-24] KAIST_INSTITUTE 3407
59 Others The 2008-3rd Forum for City of Tomorrow [2008-11-21] file KAIST_INSTITUTE 3477
58 Others 제 7회 KIUSS 미래도시포럼 [2007-10-12] KAIST_INSTITUTE 3489
57 KIITC KAIST-LG전자 공동협력 워크샵 [2007-06-05] KAIST_INSTITUTE 3494
56 Others 제 8회 KIUSS 미래도시포럼 [2007-10-18] KAIST_INSTITUTE 3510
55 Others The 2nd KIUSS Seminar [2008-06-23] file KAIST_INSTITUTE 3529
54 Others KAIST-화이자제약(주) Strategy Alliance 모색 회의 [2007-04-25] KAIST_INSTITUTE 3559
53 KIB 총장님 초청 KI for BioCentury 세미나 [2007-01-03] KAIST_INSTITUTE 3644
52 Others 제 9회 KIUSS 미래도시포럼 [2007-12-13] KAIST_INSTITUTE 3670
51 Others The 2008-3rd KIUSS Forum for City of Tomorrow [2008-07-22] file KAIST_INSTITUTE 3748
50 Others 제 5회 KIUSS 미래도시포럼 [2007-08-23] KAIST_INSTITUTE 3765
49 KI KAIST Institute-삼성종합기술원 워크샵 [2007-05-02] file KAIST_INSTITUTE 3812
48 KIITC KAIST IT 융합연구소-삼성전자 통신연구소 협력 워크샵 [2007-04-05] KAIST_INSTITUTE 3831
47 Others 제 3회 KIUSS 미래도시 포럼 [2007-06-07] KAIST_INSTITUTE 3831
46 Others 제 6회 KIUSS 미래도시포럼 [2007-09-20] KAIST_INSTITUTE 3845
45 KI KI Workshop for New Faculty [2008-03-11] KAIST_INSTITUTE 3859
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