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1. Title: [KIB] Peptide Self-Assembly: From Neurodegenerative Diseases to Novel Nanomaterials
 

2. Date and Time: Thursday, May 22, 2008, 16:00 ~ 17:00

 
3. Place: Room 2113, Biomedical Research Center (E7)
 

4. Speaker: Prof. Chan Beum Park (Dept. of Materials Science & Engineering, KAIST)
                 Ph.D. in Chemical Engineering from POSTECH, 1999
                 Lab. homepage: http://biomaterials.kaist.ac.kr
                 Research interests include self-assembled biomaterials,

                 artificial photosynthesis, cofactor regeneration, biosensors & biochips,
                 nanotoxicology, biofunctionalized nanomaterials, etc.


5. Abstract
Self-assembly, a process in which small building blocks spontaneously form fine structures, is centrally important in life and has a great potential for fabricating novel materials as well. The self-assembly of peptides into amyloid aggregates is a pathological hallmark of many neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow, and other life-threatening diseases. Despite many studies on amyloid over a century, a clear understanding on how normal and soluble peptides assemble into amyloid aggregates remains unresolved. In this seminar, following topics about amyloid self-assembly will be discussed:


1) template-directed formation of amyloid aggregates, 2) amyloid lawn system for high-throughput analysis of amyloid toxicity and drug screening. From an engineering point of view, the self-assembly of peptide-based building blocks into nanostructures is an attractive route for fabricating novel bio-inspired materials because of their capacity for molecular recognition and functional flexibility as well as the mild conditions required in the fabrication process. I will introduce our recent development of a novel process for solid-phase growth of vertically well-aligned peptide nanowires having a high aspect ratio and a long persistence length.





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60 KINC KI Seminar [2008-11-11] file KAIST_INSTITUTE 29101
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57 FIRIC KAIST Fourth Industrial Revolution Intelligence Center (FIRIC) Held Joint Workshop with EU JRC file KAIST_INSTITUTE 17471
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51 KI the 1st Exhibition of Space K, Melting Point [2012-03-09] file KAIST_INSTITUTE 10681
50 KI 2011 KAIST Institute International Workshop on Smart Media [2011-09-27] file KAIST_INSTITUTE 10247
49 KIHST Launching Symposium of KI for Health Science and Technology [2016-06-03] file KAIST_INSTITUTE 9492
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46 KI KAIST Institute International Forum [2010-10-28] file KAIST_INSTITUTE 8311
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44 KI KAIST-CORNELL University Joint Workshop on Nanotechnology [2012-10-16] file KAIST_INSTITUTE 7140
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