KI for BioCentury

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Total 18

Optogenetic Control of Endogenous Ca2+ Channels in Vivo

Memory improvement by light-elevated concentration of calcium ions proven for the first time in the world “This study proved th...

2015-12-31

Formation and Re-formation of the Complex of the Disease-rela...

Opening a new prospect for the treatment of neurodegenerative disease "The AXH domain of ATXN1 and Capicua (CIC) complex structu...

2013-12-31

Blue-light Twirls LARIAT. Let’s Hunt Running Proteins in Cells!

The precise inhibition of target proteins can serve as an effective means to dissect complex signaling networks or identify new the...

2014-10-17

Light-activated Reversible Inhibition by Assembled Trap (LARI...

A unique optogenetic technology to uncover the secrets of the brain “Optogenetics represent the best technology for understan...

2014-12-31

A New Epigenetic Player in Melanoma Tumor Progression and Met...

"A new study reveals how JMJD3, a histone demethylase protein, promotes tumor by regulating methylation status of a specific target...

2016-05-02

Structure of Huntington’s Disease Protein Unveiled

A group led by Professor Ji-Joon Song at KAIST Institute of BioCentury revealed the 3 dimensional structure of proteins that cause ...

2016-10-12

Determination of Huntington's disease Protein

Study on the 3D Structure of the Huntington Protein Using Electron Microscopy Huntington’s disease, also known as Huntington’s c...

2017-02-28

Cancer Nanomedicine for Combined Photoacoustic Imaging and Ph...

A new class of photonic nanomaterial with biodegradability and biocompatibility is developed for combined photoacoustic imaging and...

2018-05-10

Development of peptide-based remedy to treat psoriasis and at...

Psoriasis, a chronic inflammatory skin disease, is an autoimmune disease that about 3% of adults in the world suffer from. Recently...

2019-02-28

A Peptide-Antibody Hybrid Platform for Targeted Cancer Therapy

Synergy in hybrid-A new hybrid platform is developed based on a hapten-labeled bispecific peptide and an anti-hapten antibody to ov...

2019-04-10

Noninvasive Optical Activation of Flp Recombinase in Deep Mou...

Spatiotemporal control of gene expression or labeling is a valuable strategy for identifying functions of genes within complex neur...

2019-04-10

A Novel Mechanism of Nucleosome Recognition and Destabilizati...

Ji-Joon Song’s research team revealed the working mechanism of DOT1L-Leukemia Related Protein, which recognize the histone code and...

2019-10-14

New technology for optogenetic activation of intracellular an...

The immune system defends our body against infection and disease. Antibodies are Y-shaped proteins that play a key role in immune r...

2020-02-28

Optogenetic Control of mRNA Localization and Translation in L...

A new optogenetic approach called mRNA-LARIAT enables the direct optogenetic control of localization and translation of specific mR...

2020-04-04

Team reveals protein complex structure through repeated exper...

Legionnaires’ disease, first reported in the United States, is an infectious disease that can be fatal. About 200 attendees of a 19...

2021-04-15

Revealing the molecular mechanism of a molecular motor contro...

Prof. Song’s group at the Department of Biological Sciences of KIB investigated the molecular mechanism of the CHD7 molecular motor...

2021-10-25

Computational design of a neutralizing antibody against all S...

Prof. Byung-Ha Oh’s group at KAIST has generated a therapeutic candidate for COVID-19 and emerging coronaviruses by a computational...

2022-04-25

De novo Design of a Protein Biosensor Platform Through Comput...

The organic materials, called proteins,are evolved for billion years. However, the number of the natural proteins is few. The story...

2022-03-31

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